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| 355 | Gardner JD. Triadafilopoulos G. Identifying different phenotypes of
symptomatic gastroesophageal reflux disease using artificial intelligence. medRxiv April, 2023.
| | 354 | Gardner JD. Gastric acidity in different phenotypes of symptomatic
gastroesophageal reflux disease. medRxiv April, 2023. | | 353 | Gardner JD. Decreased variation in esophageal acid concentration in
different phenotypes of symptomatic gastroesophageal reflux disease. medRxiv
April, 2023.
| | 352 | Gardner, J. D. Oscillating esophageal acid sensitivity in symptomatic reflux
hypersensitivity and functional heartburn. https://doi.org/10.32388/
IJUE1J.2. | | 351 | Gardner J.D., Sloan S., Robinson M., Miner P.B. The relationship between esophageal acidity and symptom frequency in symptomatic nonerosive gastroesophageal reflux disease Physiological Reports, 10, e15442. https://doi.org/10.14814/phy2.15442 | | 350 | Mengyu Zhang1,5; Busra Yaman1; Sabine Roman2; Edoardo Savarino3; C. Prakash Gyawali4; Jerry D. Gardner6; Daniel Sifrim1 Post-reflux swallow-induced peristaltic wave (PSPW): physiology, triggering factors and role in reflux clearance in healthy subjects | | 349 | Sonu I, Triadafilopoulos G, Gardner JD. Persistent constipation and abdominal adverse events with newer treatments for constipation. BMJ Open Gastro 2016; 3:e000094. | | 348 | Lu L, Mu JC, Sloan S, Miner Jr. PB, Gardner JD. Exploring the physiologic role of human gastroesophageal reflux by analyzing time-series data from 24-hr gastric and esophageal pH recordings. Physiological Reports 2, e12051, 2014. | | 347 | Gardner, J.D. Increased gastric acid secretion as a possible
cause of GERD. Nature Reviews Gastroenterology & Hepatology 7:125-126, 2010. | | 346 | Blondeau, K., Sifrim, D., Gardner, J.D. Continuous distal oesophageal acidification decreases
postprandial gastric acidity in healthy human subjects. Aliment Pharmacol Ther 29:561-570, 2009. | | 345 | Gerson L., Triadafilopoulos G., Sahbaie P., Young W., Sloan S., Robinson M., Miner P.B. Jr. and Gardner J.D. Time esophageal pH < 4 overestimates the prevalence of pathologic esophageal reflux in subjects with gastroesophageal reflux disease treated with proton pump inhibitors. BMC Gastroenterology 8:15-26, 2008 | | 344 | Gardner J.D. How do I interpret a positive diagnostic test? Gastrointestinal Endoscopy 66: 891-893, 2007. | | 343 | Gardner J.D., Young W., Sloan S., Robinson M., Miner P.B. Jr. The effects of changing temperature correction factors on measures of acidity calculated from gastric and oesophageal pH recordings. Aliment Pharmacol Ther 23:629-638, 2006. | | 342 | Gardner J.D., Young W., Sloan S., Robinson M., Miner P.B. Jr. The fractal nature of human gastro-oesophageal disease. Aliment Pharmacol Ther 22:823-830, 2005.
| | 341 | Gardner J.D., Sloan S., Robinson M., Miner P.B. Frequency analyses of gastric pH in control and gastro-oesophageal reflux disease subjects treated with a proton-pump inhibitor. Aliment Pharmacol Ther 20:1381-1386, 2004. | | 340 | Gardner J.D., Sloan S., Robinson M., Miner P.B. Oesophageal pH has a power-law distribution in control and gastro-oesophageal reflux disease subjects. Aliment Pharmacol Ther 20:1373-1379, 2004. | | 339 | Gardner J.D., Gallo-Torres H., Sloan S., Robinson M., Miner P.B. Jr. The basis for the decreased response to proton pump inhibitors in gastro-oesophageal reflux disease patients without erosive oesophagitis. Aliment Pharmacol Ther 18:891-905, 2003. | | 338 | Gardner J.D., Sloan S., Robinson M., Miner P.B. Jr. Heartburn severity can predict pathologic oesophageal reflux in gastro-oesophageal reflux patients treated with a proton pump inhibitor. Aliment Pharmacol Ther 18:133-140, 2003. | | 337 | Gardner, J.D., Sloan, S., Miner, P.B. Jr., Robinson, M. Determination of the reduction in gastric acidity necessary to prevent pathological oesophageal reflux in patients with gastroesophageal reflux disease treated with a proton pump inhibitor. Aliment Pharmacol Ther 17:954-964, 2003. | | 336 | Gardner, J.D., Sloan, S., Miner, P.B. Jr., Robinson, M. Meal-stimulated gastric acid secretion and integrated gastric acidity in gastroesophageal reflux disease. Aliment Pharmacol Ther 17:945-953, 2003. | | 335 | Gardner, J.D., Rodriguez-Stanley, S., Robinson, M., Miner, P.B. Jr. Cisapride inhibits meal-stimulated gastric acid secretion and postprandial gastric acidity in subjects with gastroesophageal reflux disease. Aliment Pharmacol Ther 16:1819-1829, 2002. | | 334 | Gardner, J.D., Ciociola, A.A., Robinson, M, McIsaac, R.L. Determination of the time of onset of action of ranitidine and famotidine on gastric acidity. Aliment Pharmacol Ther 16:1-11, 2002. | | 333 | Gardner, J.D., Ciociola, A.A., Robinson, M. Measurement of meal-stimulated gastric acid secretion by in vivo gastric autotitration. J. Appl. Physiol. 92: 427-434, 2002 | | 332 | Robinson, M., Rodriguez-Stanley, S., Ciociola, A.A., Filinto, J., Zubaidi, S, Miner, P.B. Jr., Gardner, J.D. Control of nocturnal gastric acidity: a role for low dose bedtime ranitidine to supplement daily omeprazole. Dig. Dis. Sci. 47: 265-273, 2002. | | 331 | Gardner, J.D., Perdomo, C., Sloan, S., Hahne, W.F., Barth, J.A., Rodriguez-Stanley, S., and Robinson, M. Integrated acidity and rabeprazole pharmacology. Aliment. Pharmacol. Ther. 16: 455-464,2002. | | 330 | Gardner, J.D., Rodriguez-Stanley, S., and Robinson, M. Integrated acidity and the pathophysiology of GERD. Am. J. Gastroenterol. 96: 1363-1370, 2001. | | 329 | Robinson, M., Rodriguez-Stanley, S., Ciociola, A.A., Filinto, J., Zubaidi, S, Miner, P..B. Jr., Gardner, J.D. Synergy between low dose ranitidine and antacid in reducing gastric and esophageal acidity and relieving meal-induced heartburn. Aliment. Pharmacol. Ther. 15: 1365-1374, 2001. | | 328 | Joshi, S. N. and Gardner, J.D. Gastrin and colon cancer: A unifying hypothesis. Dig, Dis. 14: 334-344, 1996. | | 327 | Bastani, B., Yang, L., Baldassare, J.J., Pollo, D.A. and Gardner, J.D. Cellular distributions of isoforms of protein kinase C (PKC) in pancreatic acini. Biochim. Biophys. Acta. 1269: 307-315, 1995. | | 326 | Huang, S-C., Talkad, V.D., Fortune, K.P., Jonnalagadda, S., Severi, C., Delle Fave, G. and Gardner, J.D. Modulation of cholecystokinin activity by albumin. Proc. Natl. Acad. Sci. USA. 92: 10312-10316, 1995. | | 325 | Huang, S-C., Fortune, K.P., Wank, S.A., Kopin, A.S. and Gardner, J.D. Multiple affinity states of different cholecystokinin (CCK) receptors. J. Biol. Chem. 269: 26121-26126, 1994 | | 324 | Pollo, D.A., Baldassare, J.J., Honda, T., Henderson, P.A., Talkad, V.D. and Gardner, J.D. Effects of cholecystokinin (CCK) and other secretagogues on isoforms of protein kinase C (PKC) in pancreatic acini. Biochim. Biophys. Acta. 1224: 127-138, 1994. | | 323 | Pandya, P.K., Huang, S-C., Talkad, V.D., Wank, S.A. and Gardner, J.D. Biochemical regulation of the three different states of the cholecystokinin (CCK) receptor in pancreatic acini. Biochim. Biophys. Acta. 1224: 117-126, 1994 | | 322 | Talkad, V.D., Patto, R.J., Metz, D.C., Turner, R.J., Fortune, K.P., Bhat, S.T. and Gardner, J.D. Characterization of the three different states of the cholecystokinin (CCK) receptor in pancreatic acini. Biochim. Biophys. Acta. 1224: 103-116, 1994. | | 321 | Talkad, V.D., Fortune, K.P., Pollo, D.A., Shah, G.N., Wank, S.A. and Gardner, J.D. Direct demonstration of three different states of the pancreatic cholecystokinin receptor. Proc. Natl. Acad. Sci. USA. 91: 1868-1872, 1994. | | 320 | Metz, D.C., Pradhan, T.K., Mrozinski, J.E., Jr., Jensen, R.T., Turner, R.J., Patto, R.J. and Gardner, J.D. Effect of inhibition of microsomal Ca2+-ATPase on cytoplasmic calcium and enzyme secretion in pancreatic acini. Biochim. Biophys. Acta. 1220: 199-208, 1994. | | 319 | Bhat, S.T., Talkad, V., Pollo, D.A. and Gardner, J.D. Characterization of a persistent inhibitory action of L-364,718 on cholecystokinin-stimulated enzyme secretion in pancreatic acini. Pancreas. 9: 101-108, 1994. | | 318 | Silen, M.L. and Gardner, J.D. Gastrointestinal peptides and cancer. Trends Endocrinol. Metab. 4: 131-135, 1993. | | 317 | Bhat, S.T., Vinayek, R., Jensen, R.T. and Gardner, J.D. A newly recognized action of cholecystokinin on pancreatic acini-release of lactate dehydrogenase. Biochim. Biophys. Acta. 1177: 208-214, 1993. | | 316 | Vinayek, R., Patto, R.J., Menozzi, D., Gregory, J., Mrozinski, J.E., Jensen, R.T. and Gardner, J.D. Occupation of low affinity cholecystokinin (CCK) receptors by CCK activates signal transduction and stimulates amylase secretion in pancreatic acinar cells. Biochim. Biophys. Acta. 1176: 183-191, 1993. | | 315 | Presti, M.E. and Gardner, J.D. Receptor antagonists for gastrointestinal peptides. Am. J. Physiol. 264: G399-G406, 1993. | | 314 | Metz, D.C., Pisegna, J.R., Ringham, G.L., Fishbeyn, V.A., Benya, R.V., Gardner, J.D. and Jensen, R.T. Prospective study of efficacy and safety of lansoprazole in Zollinger-Ellison Syndrome (ZES). Dig. Dis. Sci. 38: 245-256, 1993.
| | 313 | Jensen, R.T. and Gardner., J.D. Gastrinoma. In: The Exocrine Pancreas: Biology, Pathobiology and Diseases: 2nd Ed., Chapter 49. (V.L.W. Go, F.P. Brooks, E.P. DiMagno, J.D. Gardner, E. Lebenthal and G.A.Scheele, eds.). Raven Press Publishing Co., New York, N.Y., 1993, pp. 931-978. | | 312 | Gardner, J.D. and Jensen., R.T. Receptors for secretagogues on pancreatic acinar cells. In: The Exocrine Pancreas: Biology, Pathobiology and Diseases: 2nd Ed., Chapter 9. (V.L.W. Go, F.P. Brooks, E.P. DiMagno, J.D. Gardner, E. Lebenthal and G.S. Scheele, eds.). Raven Press Publishing Co., New York, N.Y., 1993, pp. 151-166.
| | 311 | Yuan, D.S., Wank, S.A. and Gardner, J.D. Cibacron blue-induced enhancement of agonist binding to cholecystokinin (CCK) receptors in solubilized pancreatic membranes. Biochim. Biophys. Acta. 1146: 52-58, 1993. | | 310 | Slimak, G.G., Stark, H.A., Egan, J.J., Jensen, R.T. and Gardner, J.D. Effect of verapamil on the cyclic AMP-mediated pathway for amylase secretion in rat pancreatic acini. Pancreas 8: 212-219, 1993. | | 309 | Helander, H.F., Rutgersson, K., Helander, K.G., Gardner, J.D., Jensen, R.T. and Maton, P.N. Stereologic investigations of human gastric mucosa: II. Oxyntic mucosa from patients with Zollinger-Ellison syndrome. Scand. J. Gastroenterology 27: 875-883, 1992. | | 308 | Metz, D.C., Patto, R.J., Mrozinski, J.E. Jr., Jensen, R.T., Turner, R.J. and Gardner, J.D. Thapsigargin defines the roles of cellular calcium in secretagogue-stimulated enzyme secretion from pancreatic acini. J. Biol. Chem. 267: 20620-20629, 1992. | | 307 | Patto, R.J., Vinayek, R., Jensen, R.T. and Gardner, J.D. Carbachol does not down-regulate substance P receptors in pancreatic acini. Pancreas 7: 447-452, 1992. | | 306 | Pisegna, J.R., Norton, J.A., Slimak, G.G., Metz, D.C., Maton, P.N., Gardner, J.D. and Jensen, R.T. Effects of curative gastrinoma resection on gastric secretory function and antisecretory drug requirement in the Zollinger-Ellison syndrome. Gastroenterology 102: 776-778, 1992. | | 305 | Jensen, R.T. and Gardner, J.D. Zollinger-Ellison syndrome: Clinical presentation, pathology, diagnosis and treatment. In: Peptic ulcer and other acid-related diseases. (A. Dannenberg, D. Zakim, eds.). Academic Research Associates, Armonk, NY, 1991, pp.117-212. | | 304 | Rusconi, L. De Castiglione, R., Gozzini, L., Ciomei, M., Molinari, I., Basilico, L., Rubino, T., Vinayek, R. and Gardner, J.D. Bombesin Receptor Antagonists. Analogues based on substance P antagonists. Il Farmaco 46: 725-742, 1991. | | 303 | Vinayek, R., Amantea, M.A., Maton, P.N., Frucht, H., Gardner, J.D. and Jensen, R.T. Pharmacokinetics of oral and intravenous omeprazole in patients with Zollinger-Ellison syndrome. Gastroenterology 101: 138-147, 1991. | | 302 | Menozzi, D., Vinayek, R., Jensen, R.T. and Gardner, J.D. Down-regulation and recycling of high affinity cholecystokinin receptors on pancreatic acinar cells. J. Biol. Chem. 266: 10385-10391, 1991. | | 301 | Jensen, R.T. and Gardner, J.D. Cholecystokinin receptor antagonists in vitro. In: Cholecystokinin antagonists in gastroenterology: basic and clinical status. (C. Beglinger, G. Adler, eds). Springer-Verlag GmbH and Co., Heidelberg, West Germany, 1991, pp.93-111. | | 300 | London, J.F., Shawker, T.H., Doppman, J.L., Miller, D.L., Frucht, H., Vinayek, R., Stark, H.A., Miller, L.S., Norton, J. A., Jensen, R.T., Gardner, J.D. and Maton, P.N. Prospective assessment of abdominal ultrasound in patients with Zollinger-Ellison syndrome. Radiology 178: 763-767, 1991. | | 299 | Waxman, I., Gardner, J.D., Jensen, R.T. and Maton, P.N. Peptic ulcer perforation as the presentation of Zollinger-Ellison syndrome. Dig. Dis. Sci. 36: 19-24, 1991. | | 298 | Miller, L., Gardner, J.D. Doppman, J.L. and Jensen, R.T. Zollinger-Ellison syndrome. In: Handbook of Experimental Pharmacology. (M.J. Collen, S.B. Benjamin, eds.). Springer-Verlag GmbH and Co., Heidelberg, West Germany, 1991, pp.349-400. | | 297 | Huang, S-C., Yu, D-H., Wank, S.A., Gardner, J.D., Jensen, R.T. Characterization of the bombesin receptor on mouse pancreatic acini by chemical cross-linking. Peptides 11: 1143-1150, 1990. | | 296 | Frucht, H., Norton, J.A., London, J.F., Vinayek, R., Doppman, J.L., Gardner, J.D., Jensen, R.T. and Maton, P.N. Detection of duodenal gastrinomas by operative endoscopic transillumination: a prospective study. Gastroenterology 99: 1622-1627, 1990. | | 295 | Chiang, H-C.V., O'Dorisio, T.M., Huang, S-C., Maton, P.N., Gardner, J.D. and Jensen, R.T. Multiple hormone elevations in Zollinger-Ellison syndrome: prospective study of clinical significance and of the development of a second symptomatic pancreatic endocrine tumor syndrome. Gastroenterology 99: 1565-1575, 1990. | | 294 | Maton, P.N., Lack, E.E., Colleen, M.J., Cornelius, M.J., David, E., Gardner, J.D. and Jensen, R.T. The effect of Zollinger-Ellison syndrome and omeprazole therapy on gastric oxyntic endocrine cells. Gastroenterology 99: 943-950, 1990. | | 293 | Rowley, W.H., Sato, S., Huang, S-C., Collado-Escobar, D.M., Beaven, M.A., Wang, L-H., Martinez, J., Gardner, J.D. and Jensen, R.T. Cholecystokinin-induced formation of inositol phosphates in pancreatic acini. Am. J. Physiol. 259: G655-G665, 1990. | | 292 | Vinayek, R., Murakami, M., Sharp, C.M., Jensen, R.T. and Gardner, J.D. Carbachol desensitizes pancreatic enzyme secretion by down-regulation of receptors. Am. J. Physiol. 258: G107-121, 1990. | | 291 | Vinayek, R., Murakami, M., Sharp, C., Jensen, R.T. and Gardner, J.D. Carbachol-induced down-regulation of receptors for pancreatic secretagogues. Digestion 46: 112-124, 1990. | | 290 | Maton, P.N., Pradhan, T., Zhou, Z-C., Gardner, J.D. and Jensen, R.T. Activities of calcitonin gene-related peptide (CGRP) and related peptides at the CGRP receptor. Peptides 11: 485-489, 1990. | | 289 | Menozzi, D., Jensen, R.T. and Gardner, J.D. Dispersed pancreatic acinar cells and pancreatic acini. In: Methods in Enzymology, 192. (S. Fleischer and B. Fleischer, eds.). Academic Press, Inc., New York, NY, 1990, pp.271-279. | | 288 | Wank, S.A., Jensen, R.T. and Gardner, J.D. Stimulation of secretion by secretagogues. In: Methods in Enzymology, 192. (S. Fleischer and B. Fleischer, eds.). Academic Press, Inc., New York, NY, 1990, pp.247-255 | | 287 | Vinayek, R. and Gardner, J.D. Receptor identification. In: Methods in Enzymology, 191. (S. Fleischer and B. Fleischer, eds.). Academic Press, Inc., New York, NY, 1990, pp.609-639. | | 286 | Sutliff, V.E., Cherner, J.A., Jensen, R.T. and Gardner, J.D. Binding of
125I-CCK-8 and 125I-gastrin-I to dispersed chief cells from guinea pig stomach. Biochim. Biophys. Acta. 1052: 9-16, 1990.
| | 285 | Miller, L.S., Vinayek, R., Frucht, H., Gardner, J.D., Jensen, R.T. and Maton, P.N. Reflux esophagitis in patients with Zollinger-Ellison syndrome. Gastroenterology 98: 341-346, 1990. | | 284 | Yu, D-H., Wank, S.A., Mantey, S., Gardner, J.D. and Jensen, R.T. Pancreatic receptors for cholecystokinin: evidence for three receptor classes. Am. J. Physiol. 258: G86-G95, 1990. | | 283 | Cox, K.L., von Schrenck, T., Moran, T.H., Gardner, J.D. and Jensen, R.T. Characterization of cholecystokinin receptors in the sphincter of Oddi. Am. J. Physiol. 257: G873-G881, 1990. | | 282 | Wank, S.A., Jensen, R.T. and Gardner, J.D. Pancreatic secretion at the cellular level. In: Current Topics in Gastroenterology and Hepatology. (G.N.J. Tytgat and M. van Blankenstein, eds.). Georg Thieme Verlag, Thieme Medical Publishers Inc., Stuttgart, New York, 1990, pp.428-436. | | 281 | Jensen, R.T., Huang, S.C., von Schrenck, T., Wank, S.A. and Gardner, J.D. Cholecystokinin (CCK) receptor antagonists: ability to distinguish various classes of CCK receptors. In: GI Endocrinology: Receptors and post-receptor mechanisms. (J.C. Thompson, ed.). Academic Press, Inc., New York, NY, 1990, pp.95-113. | | 280 | Vinayek, R., Frucht, H., London, J.F., Miller, L.S., Stark, H.A., Norton, J.A., Cederberg, C., Jensen, R.T., Gardner, J.D. and Maton, P.N. The use of intravenous omeprazole in patients with Zollinger-Ellison syndrome undergoing surgery. Gastroenterology 99: 10-16, 1990. | | 279 | Doppman, J.L. Miller, D.L., Chang, R., Maton, P.N., London, J.F., Frucht, H., Gardner, J.D., Jensen, R.T. and Norton J.A. Gastrinomas: Localization by means of selective intraarterial injection of secretin. Radiology 174: 25-29, 1990. | | 278 | Gardner, J.D. and Jensen, R.T. Role of receptors in expression of gastrointestinal hormone function. In: GI Endocrinology: Receptors and post-receptor mechanisms. (J.C. Thompson, ed.). Academic Press, Inc., New York, NY, 1990, pp.1-12. | | 277 | Vinayek, R., Frucht, H., Chiang, H-C.V., Maton, P.N., Gardner, J.D. and Jensen, R.T. Zollinger-Ellison syndrome: recent advances in the management of the gastrinoma. In: Gastroenterology Clinics of North America, 19. (R.T. Jensen, ed.). W.B. Saunders Co., Philadelphia, PA, 1990, pp.197-217. | | 276 | Jensen, R.T., Wank, S.A., Rowley, W.H., Sato, S. and Gardner, J.D. Interactions of CCK with pancreatic acinar cells. Trends Pharmacol. Sci. 10: 418-423, 1989. | | 275 | Coy, D.H., Taylor, J.E., Jiang, N-Y., Kim, S.H., Wang, L-H., Chiang, S.C., Moreau, J-P., Gardner, J.D. and Jensen, R.T. Short-chain pseudopeptide bombesin receptor antagonists with enhanced binding affinities for pancreatic acinar and Swiss 3T3 cells display strong antimitotic activity. J. Biol. Chem. 264: 14691-14697, 1989. | | 274 | Frucht, H., Howard, J.M., McCarthy, D.M., Maton, P.N., Stark, H.A., Gardner, J.D. and Jensen, R.T. Prospective study of the standard meal provocative test in Zollinger-Ellison syndrome. Am. J. Med. 87: 528-536, 1989. | | 273 | London, J.F., Doppman, J.D., Maton, P.N., Gardner, J.D. and Jensen, R.T. Zollinger-Ellison syndrome in the intensive care setting. J. Intensive Care Med. 4: 272-283, 1989. | | 272 | Sheppard, B.C., Norton, J.A., Doppman, J.L., Maton, P.N., Gardner, J.D. and Jensen, R.T. Management of islet cell tumors in patients with multiple endocrine neoplasia (MEN): a prospective study. Surgery 106: 1108-1117, 1989. | | 271 | Maton, P.N., Gardner, J.D. and Jensen, R.T. Recent advances in management of gastric acid hypersecretion in patients with Zollinger-Ellison syndrome. In: Gastroenterology Clinics of North America. (R.T. Jensen, ed.). W.B. Saunders Co., Philadelphia, PA, 1989, 18: 847-863. | | 270 | Jensen, R.T., von Schrenck, T., Yu, D-H., Wank, S.A. and Gardner, J.D. Pancreatic cholecystokinin (CCK) receptors: comparison with other classes of CCK receptors. In: The Neuropeptide Cholecystokinin (CCK). (Hughes, Dockray and Woodruff, eds.). Ellis Horwood, Ltd., West Sussex, England, 1989, pp.150-162 | | 269 | Maton, P.N., Vinayek, R., Frucht, H., McArthur, K.A., Miller, L.S., Saeed, Z.A., Gardner, J.D. and Jensen, R.T. Long-term efficacy and safety of omeprazole in patients with Zollinger-Ellison syndrome: a prospective study. Gastroenterology 97: 827-836, 1989. | | 268 | Qian, J-M., Coy, C.H., Jiang, N.Y., Gardner, J.D. and Jensen, R.T. Reduced peptide bond pseudopeptide analogues of substance P. J. Biol. Chem. 264: 16667-16671, 1989. | | 267 | Maton, P.N., Lack, E., Vinayek, R., Collen, M.J., Frucht, H., Miller, L.S., Gardner, J.D. and Jensen, R.T. Prospective assessment of the safety and efficacy of long-term omeprazole therapy in patients with Zollinger-Ellison syndrome. Scand. J. Gastroenterol 24: 181, 1989. | | 266 | Frucht, H., Howard, J.M., Slaff, J.I., McCarthy, D.M., Maton, P.N., Wank, S.A., Vinayek, R., Gardner, J.D. and Jensen, R.T. Secretin and calcium provocative tests in Zollinger-Ellison syndrome. Ann. Int. Med. 111: 713-722, 1989. | | 265 | Saeed, Z.A., Huang, S.C., Coy, D.H., Jiang, N.Y., Heinz-Erian, P., Mantey, S., Gardner, J.D. and Jensen, R.T. Effect of substitutions in position 12 of bombesin on antagonist activity. Peptides 10: 597-603, 1989. | | 264 | Menozzi, D., Stark, H.A., Martinez, J., Jensen, R.T. and Gardner, J.D. Cholecystokinin (CCK)-induced desensitization of pancreatic enzyme secretion is mediated by low-affinity CCK receptors. Peptides 10: 337-341, 1989. | | 263 | Maton, P.N., Norton, J.A., Nieman, L., Doppman, J.L., Gardner, J.D. and Jensen, R.T. Multiple endocrine neoplasia Type-2 with Zollinger-Ellison syndrome caused by solitary pancreatic gastrinoma. JAMA 262: 535-537, 1989. | | 262 | Murakami, M., Vinayek, R., Jensen, R.T. and Gardner, J.D. Carbachol-induced down-regulation of high affinity receptors for vasoactive intestinal peptide. Am. J. Physiol. 257: G402-G408, 1989 | | 261 | Sutliff, V.E., Rattan, S., Gardner, J.D. and Jensen, R.T. Characterization of cholinergic receptors mediating pepsinogen secretion from chief cells. Am. J. Physiol. 257: G226-G234, 1989. | | 260 | Huang, S.C., Zhang, L., Chiang, H-C.V., Wank, S.A., Maton, P.N., Gardner, J.D. and Jensen, R.T. Benzodiazepine analogues L365,260 and L364,718 as gastrin and pancreatic CCK receptor antagonists. Am. J. Physiol. 257: G169-G174, 1989. | | 259 | Menozzi, D., Gardner, J.D., Jensen, R.T. and Maton. P.N. Properties of receptors for gastrin and cholecystokinin on gastric smooth muscle cells. Am. J. Physiol. 257: G73-G79, 1989.
| | 258 | Huang, S-C., Yu, D-H., Wank, S.A., Mantey, S., Gardner, J.D, and Jensen, R.T. Importance of sulfation of gastrin or cholecystokinin (CCK) on affinity for gastrin and CCK receptors. Peptides 10: 785-789, 1989. | | 257 | Maton, P.N., Mackem, S.H., Norton, J.A., Gardner, J.D., O'Dorisio, T.M. and Jensen, R.T. Ovarian carcinoma as a cause of Zollinger-Ellison syndrome: Natural history, secretory products and response to provocative tests. Gastroenterology 97: 468-471, 1989. | | 256 | Gardner, J.D. and Jensen, R.T. Pancreatic acini as second messenger models in exocrine secretion. In: Methods in Enzymology, Biomembranes and Biological Transport. (S. Fleischer and B. Fleischer, eds.). Academic Press, Inc., New York, NY, 1989, pp.590-594. | | 255 | Gardner, J.D. and Jensen, R.T. Receptors for gut peptides and other secretagogues on pancreatic acinar cells. In: Handbook of Physiology. Am. J. Physiol. 1989, pp.171-192.
| | 254 | Coy, D.H., Heinz-Erian, P., Jiang, N-Y., Taylor, J., Moreau, J-P., Gardner, J.D. and Jensen, R.T. Progress in the development of competitive bombesin antagonists. Ann. N.Y. Acad. Sci. 547: 150-157, 1989. | | 253 | Sato, S., Stark, H.A., Martinez, J., Beaven, M.A., Jensen, R.T. and Gardner, J.D. Receptor occupation, calcium mobilization and amylase release in pancreatic acini: effect of CCK-JMV-180. Am. J. Physiol. 257: G202-G209, 1989. | | 252 | Maton, P.N., Gardner, J.D. and Jensen, R.T. Diagnosis and management of Zollinger-Ellison syndrome. In: Endocrinology and Metabolism Clinics of North America, 18. Plenum Publishing Corp., New York, NY, 1989, pp.519-543. | | 251 | Saeed, Z.A., Norton, J.A., Frank, W.O., Young, M.D., Gardner, J.D. and Jensen, R.T. Parenteral antisecretory drug therapy in patients with Zollinger-Ellison syndrome. Gastroenterology 96: 1393-1402, 1989. | | 250 | Maton, P.N., Gardner, J.D. and Jensen, R.T. Use of long-acting somatostatin analog SMS201-995 in patients with pancreatic islet cell tumors. Dig. Dis. Sci. 34: 28S-39S, 1989. | | 249 | von Schrenck, T., Heinz-Erian, P., Moran, T., Mantey, S.A., Gardner, J.D. and Jensen, R.T. Neuromedin B receptor in esophagus: evidence for subtypes of bombesin receptors. Am. J. Physiol. 256: G747-G758, 1989. | | 248 | Menozzi, D., Sato, S., Jensen, R.T. and Gardner, J.D. Cyclic GMP does not inhibit protein kinase C-mediated enzyme secretion in rat pancreatic acini. J. Biol. Chem. 264: 995-999, 1989. | | 247 | Stark, H.A., Sharp, C.M., Sutliff, V.E., Martinez, J., Jensen, R.T. and Gardner, J.D. CCK-JMV-180: A peptide that distinguishes high-affinity cholecystokinin receptors from low-affinity cholecystokinin receptors. Biochim. Biophys. Acta. 1010: 145-150, 1989. | | 246 | Younes, M., Wank, S.A., Vinayek, R., Jensen, R.T. and Gardner, J.D. Regulation of bombesin receptors on pancreatic acini by cholecystokinin. Am. J. Physiol. 256: G291-G298, 1989. | | 245 | Zhou, Z-C., Gardner, J.D. and Jensen, R.T. Interaction of peptides related to VIP and secretin with guinea pig pancreatic acini. Am. J. Physiol. 256: G283-G290, 1989. | | 244 | Gardner, J.D. and Jensen, R.T. Receptors for gut hormones. Ital. J. Gastroenterol. 20: 281-286, 1988 | | 243 | Jensen, R.T., Coy, D.H., Saeed, Z.A., Heinz-Erian, P., Mantey, S. and Gardner, J.D. Interaction of bombesin and related peptides with receptors on pancreatic acinar cells. Ann. N.Y. Acad. Sci. 547: 138-149, 1988. | | 242 | Fraker, D., Norton, J.A., Saeed, Z.A., Maton, P.N., Gardner, J.D. and Jensen, R.T. A prospective study of perioperative and postoperative control of acid hypersecretion in patients with Zollinger-Ellison syndrome undergoing gastrinoma resection. Surgery 104: 1054-1063, 1988. | | 241 | Zhang, L., Mantey, S., Jensen, R.T. and Gardner, J.D. An analogue of substance P with broad receptor antagonist activity. Biochim. Biophys. Acta. 972: 37-44, 1988. | | 240 | Jensen, R.T., Yu, D-H. and Gardner, J.D. Interaction of cholecystokinin antagonists with receptors on pancreatic acini. In: Cholecystokinin Antagonists. (R.Y. Wang, ed.). Alan R. Liss, Inc., New York, NY, 1988, pp.53-72. | | 239 | von Schrenck, T., Moran, T.H., Heinz-Erian, P., Gardner, J.D. and Jensen, R.T. Cholecystokinin receptors on gallbladder muscle and pancreatic acinar cells: a comparative study. Am. J. Physiol. 255: G512-G521, 1988. | | 238 | Saeed, Z., Doppman, J.L., Norton, J.A., Maton, P.N., Gardner, J.D. and Jensen, R.T. Gastrinoma localization in Zollinger-Ellison syndrome. Int. Med. Spec. 9: 79-99, 1988. | | 237 | Cherner, J.A., Jensen, R.T., Dubois, A., O'Dorisio, T.M., Gardner, J.D. and Metcalfe, D.D. Gastrointestinal dysfunction in systemic mastocytosis: a prospective study. Gastroenterology 95: 657-667, 1988. | | 236 | von Schrenck, T., Howard, J.M., Doppman, J.L., Norton, J.A., Smith, F., Maton, P.N., Vinayek, R., Frucht, H., Wank, S.A., Gardner, J.D. and Jensen, R.T. Prospective study of chemotherapy in patients with metastatic gastrinoma. Gastroenterology 94: 1326-1334, 1988. | | 235 | Gardner, J.D. and Jensen, R.T. Cell membrane receptors for secretagogues on pancreatic acinar cells. In: Advances in Metabolic Disorders, 2 (R. Levine and R. Luft, eds.). Academic Press, New York, NY, 1988, pp.113-140. | | 234 | von Schrenck, T., Jensen, R.T. and Gardner, J.D. Characteristics of the pancreatic acinar cell receptors with which cholecystokinin interacts to increase cyclic AMP. In: Gastrin and Cholecystokinin: Chemistry, Physiology and Pharmacology. (J-P. Bali and J-P. Martinez, eds.). Elsevier Science Publishing, Amsterdam, New York, Oxford, 1988, pp.49-56. | | 233 | Wank, S.A., Jensen, R.T. and Gardner, J.D. Kinetics of binding of cholecystokinin to pancreatic acini. Am. J. Physiol. 255: G106-G112, 1988. | | 232 | Norton, J.A., Cromack, D.T., Shawker, T.H., Doppman, J.L., Comi, R., Gorden, P., Maton, P.N., Gardner, J.D. and Jensen, R.T. Intraoperative ultrasonographic localization of islet cell tumors: a prospective comparison to palpation. Ann. Surg. 207: 160-168, 1988 | | 231 | Jensen, R.T., Heinz-Erian, P., Mantey, S., Jones, S.W. and Gardner, J.D. Characterization of ability of various substance P antagonists to inhibit action of bombesin. Am. J. Physiol. 254: G883-G890, 1988. | | 230 | Maton, P.N., Sutliff, V.E., Zhou, Z-C., Collins, S.M., Gardner, J.D. and Jensen, R.T. Characterization of receptors for calcitonin gene-related peptide on gastric smooth muscle cells. Am. J. Physiol. 254: G789-G794, 1988. | | 229 | Coy, D.H., Heinz-Erian, P., Jiang, N-Y., Sasaki, Y., Tayler, J., Moreau, J-P., Wolfrey, W.T., Gardner, J.D. and Jensen, R.T. Probing peptide backbone function in bombesin: a reduced peptide bond analogue with potent and specific antagonist activity. J. Biol. Chem. 263: 5056-5060, 1988. | | 228 | Cherner, J.A., Sutliff, V.E., Grybowski, D.A., Jensen, R.T. and Gardner, J.D. Functionally distinct receptors for cholecystokinin and gastrin on dispersed chief cells from guinea pig stomach. Am. J. Physiol. 254: G151-G155, 1988. | | 227 | Maton, P.N., Frucht, H., Vinayek, R., Wank, S.A., Gardner, J.D. and Jensen, R.T. Medical management of patients with Zollinger-Ellison syndrome who have had previous gastric surgery: a prospective study. Gastroenterology 94: 294-299, 1988. | | 226 | Norton, J.A., Doppman, J.L., Cornelius, M.J., Maton, P.N., Gardner, J.D. and Jensen, R.T. Effect of parathyroidectomy in patients with hyperparathyroidism and Zollinger-Ellison syndrome and multiple endocrine neoplasia Type I. Surgery 101: 958-966, 1987. | | 225 | Yu, D-H., Noguchi, M., Zhou, Z-C., Villanueva, M.L., Gardner, J.D. and Jensen, R.T. Characterization of gastrin receptors on guinea pig pancreatic acini. Am. J. Physiol. 253: G793-G801, 1987. | | 224 | Younes, M., Jensen, R.T. and Gardner, J.D. Cholecystokinin-induced residual stimulation of enzyme secretion from mouse pancreatic acini. Biochim. Biophys. Acta. 930: 410-418, 1987 | | 223 | Jensen, R.T. and Gardner, J.D. Gastrinoma. In: Current Therapy in Internal Medicine, 2. (T.M. Bayless, M.C. Brain and R.M. Cherniack, eds.). B.C. Decker, Inc., Philadelphia, PA, 1987, pp.626-629. | | 222 | Zhou, Z-C., Gardner, J.D. and Jensen, R.T. Receptors for vasoactive intestinal peptide and secretin on guinea pig pancreatic acini. Peptides 8: 633-637, 1987. | | 221 | McArthur, K.E., Raufman, J-P., Seaman, J.J., Ziemniak, J.A., Collen, M.J., Gardner, J.D. and Jensen, R.T. Cimetidine pharmacodynamics in patients with Zollinger-Ellison syndrome. Gastroenterology 93: 69-76, 1987. | | 220 | Howard, J.M., Vinayek, R., Maton, P.N., Wank, S.A., Gardner, J.D. and Jensen, R.T. Famotidine: effective treatment of Zollinger-Ellison syndrome. J. Clin. Gastroenterol. 9:23-25, 1987.
| | 219 | McArthur, K.E., Wood, C.L., O'Dorisio, M.S., Zhou, Z-C., Gardner, J.D. and Jensen, R.T. Characterization of receptors for VIP on pancreatic acinar cell membranes using covalent cross-linking. Am. J. Physiol. 252: G404-G412, 1987. | | 218 | Heinz-Erian, P., Coy, D.H., Tamura, M., Lance, V., Gardner, J.D. and Jensen, R.T. Bombesin analogues: a new class of bombesin receptor antagonists. Am. J. Physiol. 252: G439-G442, 1987. | | 217 | Maton, P.N., Miller, D.L., Doppman, J.L., Collen, M.J., Norton, J.A., Vinayek, R., Slaff, J.I., Wank, S.A., Gardner, J.D. and Jensen, R.T. Role of selective angiography in the management of patients with Zollinger-Ellison syndrome. Gastroenterology 92: 913-918, 1987. | | 216 | Wank, S.A., Doppman, J.L., Miller, D.L., Collen, M.J., Maton, P.N., Vinayek, R., Norton, J.A., Gardner, J.D. and Jensen, R.T. Prospective study of the ability of computerized axial tomography to localize gastrinomas in patients with Zollinger-Ellison syndrome. Gastroenterology 92: 905-912, 1987. | | 215 | Vinayek, R., Jensen, R.T. and Gardner, J.D. Role of sulfate ester in influencing biologic activity of cholecystokinin-related peptides. Am. J. Physiol. 252: G178-G181, 1987. | | 214 | Gardner, J.D. and Jensen, R.T. Secretagogue receptors on pancreatic acinar cells. In: Physiology of the Gastrointestinal Tract. 2nd edition (L.R. Johnson, J. Christensen, M.J. Jackson, E.D. Jacobsen and J.H. Walsh, eds.). Raven Press, New York, N.Y., 1987, pp.1109-1127. | | 213 | Cherner, J.A., Doppman, J.L., Norton, J.A., Miller, D.L., Krudy, A.G., Harmon, J.W., Raufman, J-P., Collen, M.J., Maton, P.N., Gardner, J.D. and Jensen, R.T. Prospective assessment of selective venous sampling for gastrin to localize gastrinomas. Ann. Int. Med. 105: 841-847, 1986. | | 212 | Vinayek, R., Howard, J.M., Maton. P.N., Wank, S.A., Slaff, J.I., Gardner, J.D. and Jensen, R.T. Famotidine in the therapy of gastric hypersecretory states. Am. J. Med. 81: 49-60, 1986. | | 211 | Jensen, R.T., Zhou, Z-C., Murphy, R.P., Jones, S.W., Setnikar, I., Rovati, L.A. and Gardner, J.D. Structural features of various proglumide-related cholecystokinin receptor antagonists. Am. J. Physiol. 251: G839-G846, 1986. | | 210 | Zhou, Z-C., Villanueva, M.L., Noguchi, M., Jones, S.W., Gardner, J.D. and Jensen, R.T. Mechanism of action of calcitonin gene-related peptide in stimulating pancreatic enzyme secretion. Am. J. Physiol. 251: G391-G397, 1986. | | 209 | Maton, P.N., Gardner, J.D. and Jensen, R.T. The incidence and etiology of Cushing's syndrome in patients with Zollinger-Ellison syndrome. N. Engl. J. Med. 315: 1-5, 1986. | | 208 | Howard, J.M., Chremos, A.N., Cornelius, M.J., Collen, M.J., Maton, P.N., Gardner, J.D. and Jensen, R.T. Famotidin beim Zollinger-Ellison-Syndrom. In: Famotidin - ein Fortschritt in der Therapie saurebedingter Erkrankungen. (B. Simon, G. Bianchi Porro and Hans-Gerd Dammann, eds.). Georg Thieme Verlag, Stuttgart-New York, 1986, pp.82-93. | | 207 | Jensen, R.T., Maton, P.N. and Gardner, J.D. The current management of Zollinger-Ellison syndrome. Drugs 32: 188-196, 1986.
| | 206 | Norton, J.A., Doppman, J.L., Collen, M.J., Harmon, J.W., Maton, P.N., Gardner, J.D. and Jensen, R.T. Prospective study of gastrinoma localization and resection in patients with Zollinger-Ellison syndrome. Ann. Surg. 204: 468-479, 1986. | | 205 | McArthur, K.E., Collen, M.J., Cherner, M.J., Howard, J.M., Maton, P.N., Jensen, R.T. and Gardner, J.D. Omeprazole: an effective drug for Zollinger-Ellison syndrome. Scand. J. Gastroenterol 21: 182-183, 1986. | | 204 | Sutliff, V.E., Jensen, R.T. and Gardner, J.D. Actions of vasoactive intestinal peptide and secretin on chief cells prepared from guinea pig stomach. Am. J. Physiol. 251: G96-G102, 1986. | | 203 | Maton, P.N., Jensen, R.T. and Gardner, J.D. Cholecystokinin receptor antagonists. Horm. Metab. Res. 1: 2-9, 1986. | | 202 | Jensen, R.T. and Gardner, J.D. Structure-function studies of agonists and antagonists for gastrointestinal peptide receptors on pancreatic acinar cells. In: Neural and Endocrine Peptides and Receptors. (T.W. Moody, ed.). Plenum Publishing Co., New York, N.Y., 1986, pp.485-500. | | 201 | Wank, S.A., Gardner, J.D. and Jensen, R.T. When to suspect a hypersecretory syndrome. Diagnosis 8: 62-74, 1986. | | 200 | Norton, J.A., Sugarbaker, P.H., Doppman, J.L., Wesley, R.A., Maton, P.N., Gardner, J.D. and Jensen, R.T. Aggressive resection of metastatic disease in selected patients with malignant gastrinoma. Ann. Surg. 203: 352-359, 1986. | | 199 | Gardner, J.D. and Jensen, R.T. Receptors and cell activation associated with pancreatic enzyme secretion. In: Annual Review of Physiology. (R.M. Berne, ed.). Annual Reviews, Inc., Palo Alto, Ca, 1986, pp.103-117. | | 198 | Jensen, R.T., Doppman, J.L. and Gardner, J.D. Gastrinoma. In: The Exocrine Pancreas: Biology, Pathobiology and Diseases. (V.L.W. Go, F.P. Brooks, E.P. DiMagno, J.D. Gardner, E. Lebenthal and G.A. Scheele, eds.). Raven Press, New York, N.Y., 1986, pp.727-744. | | 197 | Gardner, J.D. and Jensen, R.T. Receptors mediating the actions of secretagogues on pancreatic acinar cells. In: The Exocrine Pancreas: Biology, Pathobiology and Diseases, 1985-1986. (V.L.W. Go, F.P. Brooks, E.P. DiMagno, J.D. Gardner, E. Lebenthal, and G.A. Scheele, eds.). Raven Press, New York, N.Y., 1986, pp.109-122. | | 196 | Maton, P.N., O'Dorisio, T.M., O'Dorisio, M.S., Malarkey, W.B., Gower, W.R., Gardner, J.D. and Jensen, R.T. Successful therapy of pancreatic cholera with the long-acting somatostatin analogue SMS201-995: relation between plasma concentrations of drug and clinical and biochemical responses. Scand. J. Gastroenterol 21: 181-186, 1986. | | 195 | McArthur, K.E., Jensen, R.T. and Gardner, J.D. Treatment of acid-peptic diseases by inhibition of gastric H+,K+-ATPase. In: Annual Review of Medicine, 37. (W.P. Creger, ed.). Annual Reviews, Inc., Palo Alto, Ca., 1986, pp.97-105. | | 194 | Jensen, R.T. and Gardner, J.D. Gastrinoma. In: Current Therapy in Gastroenterology and Liver Disease, 1985-1986. (T.M. Bayless, ed.). B.C. Decker, Inc., Philadelphia, Pa, 1986, pp.77-80. | | 193 | Howard, J.M., Collen, M.J., McArthur, K.E., Cherner, J.A., Maton, P.N., Gardner, J.D. and Jensen, R.T. Comparison of famotidine with ranitidine and cimetidine in the treatment of Zollinger-Ellison syndrome. Digestion 32: 59-61, 1985. | | 192 | Jensen, R.T., Murphy, R.B., Trampota, M., Schneider, L.H., Jones, S.W., Howard, J.M. and Gardner, J.D. Proglumide analogues: potent cholecystokinin receptor antagonists. Am. J. Physiol. 249: G214-G220, 1985. | | 191 | Noguchi, M., Adachi, H., Gardner, J.D. and Jensen, R.T. Calcium-activated, phospholipid-dependent protein kinase in pancreatic acinar cells. Am. J. Physiol. 248: G692-G701, 1985. | | 190 | Howard, J.M., Chremos, A.N., Collen, M.J., McArthur, K.E., Cherner, J.A., Maton, P.N., Ciarleglio, C.A., Cornelius, M.J., Gardner, J.D. and Jensen, R.T. Famotidine, a new, potent, long-acting histamine H2-receptor antagonist: Comparison with cimetidine and ranitidine in the treatment of Zollinger-Ellison syndrome. Gastroenterology 88: 1026-1033, 1985. | | 189 | Maton, P.N., O'Dorisio, T.M., Howe, B.A., McArthur, K.E., Howard, J.M., Cherner, J.A., Malarkey, W.B., Collen, M.J., Gardner, J.D. and Jensen, R.T. Effect of a long-acting somatostatin analogue (SMS 201-995) in a patient with pancreatic cholera. N. Eng. J. Med. 312: 17-21, 1985. | | 188 | Maton, P.N., Sutliff, V.E., Jensen, R.T. and Gardner, J.D. Carbobenzoxy-amino acids: requirements for cholecystokinin receptor antagonist activity. Am. J. Physiol. 248: G479-G484, 1985. | | 187 | Howard, J.M., Jensen, R.T. and Gardner, J.D. Bombesin-induced residual stimulation of amylase release from mouse pancreatic acini. Am. J. Physiol. 248: G196-G199, 1985. | | 186 | McArthur, K.E., Collen, M.J., Maton, P.N., Cherner, J.A., Howard, J.M., Ciarleglio, C.A., Cornelius, M.J., Jensen, R.T. and Gardner, J.D. Omeprazole: effective convenient therapy for Zollinger-Ellison syndrome. Gastroenterology 88: 939-944, 1985. | | 185 | Gardner, J.D., Knight, M., Sutliff, V.E. and Jensen, R.T. N-terminal fragments of CCK-26-33 as cholecystokinin receptor antagonists in guinea pig pancreatic acini. Am. J. Physiol. 248: G98-G102, 1985. | | 184 | Gardner, J.D. and Jensen, R.T. Preparation of dispersed pancreatic acinar cells and dispersed pancreatic acini. In: Methods in Enzymology. Peptide Hormone Action, 109. (L. Birnbaumer and B.W. O'Malley, eds.). Academic Press, New York, N.Y., 1985, pp.288-293. | | 183 | Jensen, R.T. and Gardner, J.D. Assay for the cholecystokinin receptor on pancreatic acini. In: Methods in Enzymology. Peptide Hormone Action, 109. (L. Birnbaumer and B.W. O'Malley, eds.). Academic Press, New York, N.Y.. 1985, pp.64-69. | | 182 | Krudy, A.G., Doppman, J.L., Jensen, R.T., Norton, J.A., Collen, M.J., Shawker, T.H., Gardner, J.D., McArthur, K.E. and Gorden, P. Localization of islet cell tumors by dynamic CT. Amer. J. Radiol. 143: 585-589, 1984. | | 181 | Knight, M., Tamminga, C.A., Ito , Y., Gardner, J.D. and Chase, T.N. Purification of a cholecystokinin fragment peptide in the horizontal flow-through coil planet centrifuge. J. Chromatog. 301: 277-281, 1984. | | 180 | Gardner, J.D. and Jensen, R.T. Characterization of receptors for gastrointestinal peptides. In: Physiology of the Gut. (J.M. Polak, S.R. Bloom, N.A. Wright and A.G. Butler, eds.). Glaxo Group Research Ltd., Ware, Herts, U.K., 1984, pp.7-18. | | 179 | Jensen, R.T. and Gardner, J.D. Receptors for secretagogues on pancreatic acinar cells. J. Pediatr. Gastroenterol. Nutr. 3: S25-S35, 1984. | | 178 | Collen, M.J., Gardner, J.D. and Jensen, R.T. The use of ranitidine in gastric hypersecretory states. In: Perspective on Therapeutics in Northern Europe - The Use of Ranitidine in Gastroenterology. Theracom, Ltd., London, 1984, pp.7-8. | | 177 | Howard, J.M., Knight, M., Jensen, R.T. and Gardner, J.D. Discovery of an analogue of cholecystokinin with partial agonist activity. Am. J. Physiol. 247: G261-G264, 1984. | | 176 | Jensen, R.T., Collen, M.J., McArthur, K.E., Howard, J.M., Maton, P.N., Cherner, J.A. and Gardner, J.D. Comparison of the effectiveness of ranitidine and cimetidine in inhibiting acid secretion in patients with gastric hypersecretory states. In: Ranitidine: Therapeutic Advances - 1984. (J.J. Misiewicz and J.R. Wood, eds.). Excerpta Medica, Amsterdam, 1984, pp. 113-143. | | 175 | Adler, G., Kern, H.F., Pan, G-Z. and Gardner, J.D. Secretagogue-induced membrane alterations in dispersed acini from rat pancreas. Eur. J. Cell Biol. 33: 234-241, 1984. | | 174 | Jensen, R.T., Jones, S.W., Folkers, K. and Gardner, J.D. A synthetic peptide that is a bombesin receptor antagonist. Nature 309: 61-63, 1984. | | 173 | Raufman, J-P., Sutliff, V.E., Kasbekar, D.K., Jensen, R.T. and Gardner, J.D. Pepsinogen secretion from dispersed chief cells from guinea pig stomach. Am. J. Physiol. 247: G95-G104, 1984. | | 172 | Bissonnette, B.M., Collen, M.J., Adachi, H., Jensen, R.T. and Gardner, J.D. Receptors for vasoactive intestinal peptide and secretin on rat pancreatic acini. Am. J. Physiol. 246: G710-G718, 1984. | | 171 | Gardner, J.D. and Jensen, R.T. Cholecystokinin receptor antagonists. Am. J. Physiol. 246: G471-G476, 1984. | | 170 | Jensen, R.T. and Gardner, J.D. The cellular basis of action of gastrointestinal peptides. In: Advances in Cyclic Nucleotide and Protein Phosphorylation Research. (P. Greengard, G.A. Robison, R. Paoletti, S. Nicosia, eds.). Raven Press, New York, N.Y., 1984, pp.375-383. | | 169 | Jensen, R.T., Jones, S.W., Lu, Y-A., Xu, J-C., Folkers, K. and Gardner, J.D. Interaction of substance P antagonists with substance P receptors on dispersed pancreatic acini. Biochim. Biophys. Acta. 804: 181-191, 1984. | | 168 | Collen, M.J., Howard, J.M., McArthur, K.E., Raufman, J-P., Cornelius, M.J., Ciarleglio, C.A., Gardner, J.D. and Jensen, R.T. Comparison of the effectiveness of ranitidine and cimetidine in inhibiting acid secretion in patients with gastric hypersecretory states. Ann. Int. Med. 100: 52-59, 1984. | | 167 | Gardner, J.D., Knight, M., Sutliff, V.E. and Jensen, R.T. Derivatives of cholecystokinin-26-32 as cholecystokinin receptor antagonists in guinea pig pancreatic acini. Am. J. Physiol. 246: G292-G295, 1984. | | 166 | Gardner, J.D. and Jensen, R.T. The significance of multiple secretagogue receptors on pancreatic acinar cells. In: Receptors and the Upper GI Tract. (B.I. Hirschowitz and J.D. Spenney, eds.). Advanced Therapeutics, Inc., New York, N.Y., 1983, pp.60-69. | | 165 | Jensen, R.T., Jones, S.W. and Gardner, J.D. Structure-function studies of N-acyl derivatives of tryptophan that function as specific cholecystokinin receptor antagonists. Biochim. Biophys. Acta. 761: 269-277, 1983. | | 164 | Martinez, J., Briet, C., Winternitz, F., Castro, B., Gardner, J.D. and Mutt, V. Synthesis and biological properties of cholecystokinin 27-32 amide. CCK-26-32 NH2: a new class of cholecystokinin receptor antagonist. In: Peptides Structure and Function. Proceedings of 8th American Peptide Symposium. (V.J. Hruby and D.H. Rich, eds.). Pierce Chemical Co., Rockford, Il, 1983, pp.673-676. | | 163 | Jensen, R.T., Pandol, S.J., Collen, M.J., Raufman, J-P. and Gardner, J.D. Diagnosis and management of the Zollinger-Ellison syndrome. J. Clin. Gastroenterol. 5: 123-131, 1983. | | 162 | Gardner, J.D. and Jensen, R.T. Characterization of receptors for gastrointestinal peptides. Scand. J. Gastroenterol. 18: 7-18, 1983 | | 161 | Pandol, S.J., Sutliff, V.E., Jones, S.W., Charlton, C.G., O'Donohue, T.L., Gardner, J.D. and Jensen, R.T. Action of natural glucagon on pancreatic acini: due to contamination by previously undescribed secretagogues. Am. J. Physiol. 245: G703-G710, 1983. | | 160 | Gardner, J.D., Sutliff, V.E., Walker, M.D. and Jensen, R.T. Effects of inhibitors of cyclic nucleotide phosphodiesterase on actions of cholecystokinin, bombesin and carbachol on pancreatic acini. Am. J. Physiol. 245: G676-G680, 1983. | | 159 | Raufman, J-P., Kasbekar, D.K., Jensen, R.T. and Gardner, J.D. Potentiation of pepsinogen secretion from dispersed glands from rat stomach. Am. J. Physiol. 245: G525-G530, 1983. | | 158 | Jensen, R.T., Charlton, C.G., Adachi, H., Jones, S,W., O'Donohue, T.L. and Gardner, J.D. Use of 125I-secretin to identify and characterize high-affinity secretin receptors on pancreatic acinar cells. Am. J. Physiol. 245: G186-G195, 1983. | | 157 | Spanarkel, M., Martinez, J., Jensen, R.T. and Gardner, J.D. Cholecystokinin-27-32-Amide: A member of a new class of cholecystokinin receptor antagonists. J. Biol. Chem. 258: 6746-6749, 1983. | | 156 | Jensen, R.T., Jones, S.W. and Gardner, J.D. COOH-terminal fragments of cholecystokinin: A new class of cholecystokinin receptor antagonists. Biochim. Biophys. Acta. 757: 250-258, 1983 | | 155 | Gardner, J.D. and Jensen, R.T. Gastrointestinal Peptides: The Basis of Action at the Cellular Level. In: Recent Progress in Hormone Research. Academic Press, 1983, pp.211-243. | | 154 | Gardner, J.D. Mechanism by which dibutyryl cyclic GMP antagonizes the action of cholecystokinin. Gastroenterology 84: 1619-1621, 1983. | | 153 | McArthur, K.E., Jensen, R.T. and Gardner, J.D. The actions of tetraethylammonium on dispersed acini from guinea pig pancreas. Biochim. Biophys. Acta. 762: 373-377, 1983. | | 152 | Jensen, R.T., Collen, M.J., Pandol, S.J., Allende, H.D., Raufman, J-P., Bissonnette, B.M., Duncan, W.C., Durgin, P.L., Gillin, J.C. and Gardner, J.D. Cimetidine-induced impotence and breast changes in patients with gastric hypersecretory states. N. Eng. J. Med. 308: 883-887, 1983. | | 151 | Collins, S.M. and Gardner, J.D. Cholecystokinin-induced contraction of dispersed smooth muscle cells from guinea pig stomach: antagonism by proglumide and glucagon. Am. J. Physiol. 243: G497-G504, 1983. | | 150 | Jensen, R.T., Gardner, J.D., Raufman, J-P., Pandol, S.J., Doppman, J.L. and Collen, M.J. Zollinger-Ellison Syndrome - Current Concepts and Management. Ann. Int. Med. 98: 59-75, 1983. | | 149 | Raufman, J-P., Collins, S.M., Pandol, S.J., Korman, L.Y., Collen, M.J., Cornelius, M.J., Feld, M.K., McCarthy, D.M., Gardner, J.D. and Jensen, R.T. Reliability of symptoms in assessing control of gastric acid secretion in patients with Zollinger-Ellison syndrome. Gastroenterology 84: 108-113, 1983. | | 148 | Kasbekar, D.K., Jensen, R.T. and Gardner, J.D. Pepsinogen secretion from dispersed glands from rabbit stomach. Am. J. Physiol. 244: G392-G396, 1983. | | 147 | Pandol, S.J., Jensen, R.T. and Gardner, J.D. Mechanism of [Tyr4]bombesin-induced desensitization in dispersed acini from guinea pig pancreas. J. Biol. Chem. 257: 12024-12029, 1982. | | 146 | Korman, L.Y., Lemp, G.F., Jackson, M.J. and Gardner, J.D. Mechanism of action of ATP on intestinal epithelial cells: cyclic AMP-mediated stimulation of active ion transport. Biochim. Biophys. Acta. 721: 47-54, 1982. | | 145 | Martinez, J., Winternitz, F., Bodanszky, M., Gardner, J.D., Walker, M.D. and Mutt, V. Synthesis and some pharmacological properties of Z-Tyr(SO3H)-Met-Gly-Trp-Met-Asp(Phe-NH2)-OH, a 32-β-Aspartyl analogue of cholecystokinin (pancreozymin) 27-33. J. Med. Chem. 25: 589-593, 1982. | | 144 | Villanueva, M.L., Martinez, J., Bodanszky, M., Collins, S.M., Jensen, R.T. and Gardner, J.D. Selective modification of the ability of cholecystokinin to cause residual stimulation of pancreatic enzyme secretion. Am. J. Physiol. 243: G214-G217, 1982. | | 143 | Jensen, R.T., Lemp, G.F. and Gardner, J.D. Interactions of COOH-terminal fragments of cholecystokinin with receptors on dispersed acini from guinea pig pancreas. J. Biol. Chem. 257: 5554-5559, 1982. | | 142 | Gardner, J.D., Korman, L.Y., Walker, M.D. and Sutliff, V.E. Effects of inhibitors of cyclic nucleotide phosphodiesterase on the actions of VIP and secretin on pancreatic acini. Am. J. Physiol. 242: G547-G551, 1982. | | 141 | Pan, G.Z., Collen, M.J. and Gardner, J.D. Action of cholera toxin on dispersed acini from rat pancreas: post-receptor modulation involving cyclic AMP and calcium. Biochim. Biophys. Acta. 720: 338-345, 1982. | | 140 | Gardner, J.D. and Jensen, R.T. Receptor modulation of calcium and cyclic AMP: differences in coupling to specific hormone-receptor complexes in cells responsive to several hormones. In: Horizons in Biochemistry and Biophysics. (L.D. Kohn, ed.). John Wiley and Sons, Ltd., New York, NY, 6, 1982, pp.277-397. | | 139 | Raufman, J-P., Jensen, R.T., Pisano, J.J. and Gardner, J.D. Actions of Gila monster venom on dispersed acini from guinea pig pancreas. Am. J. Physiol. 242: G470-G474, 1982. | | 138 | Barlas, N., Jensen, R.T. and Gardner, J.D. CCK-induced restricted stimulation of pancreatic enzyme secretion. Am. J. Physiol. 242: G464-G469, 1982. | | 137 | Collen, M.J., Sutliff, V.E., Pan, G.Z. and Gardner, J.D. Post-receptor modulation of the action of VIP and secretin on pancreatic enzyme secretion by secretagogues that cause mobilization of cellular calcium. Am. J. Physiol. 242: G423-G428, 1982. | | 136 | Villanueva, M.L., Collins, S.M., Jensen, R.T. and Gardner, J.D. Structural requirements for the action of cholecystokinin on enzyme secretion from pancreatic acini. Am. J. Physiol. 242: G416-G422, 1982. | | 135 | Gardner, J.D. and Jensen, R.T. Receptor antagonists of the actions of gastrointestinal peptides on pancreatic acinar cells. In: Hormone Antagonists. (M.K. Agarwal, ed.). Walter de Gruyter and Co., Berlin-New York, 1982, pp.527-547. | | 134 | Jensen, R.T., Lemp, G.F., Beinfeld, M.C. and Gardner, J.D. Actions of natural GIP on pancreatic acinar cells: Due to contamination with cholecystokinin. Gastroenterology 82: 20-25, 1982. | | 133 | Barlas, N., Jensen, R.T., Beinfeld, M.C. and Gardner, J.D. Cyclic nucleotide antagonists of cholecystokinin: structural requirements for interaction with the cholecystokinin receptor. Am. J. Physiol. 242: G161-G167, 1982. | | 132 | Martinez, J., Winternitz, F., Gardner, J.D. and Mutt, V. Synthesis of new active analogs of the C-terminal heptapeptide of CCK-27-33, role of the residue in position 32 in biological activities. In: Peptides, Proc. of the 7th American Peptide Symposium. (D.H. Rich and E. Gross, eds.). Pierce Chemical Co., Rockford, Il., 1981, pp.649-652. | | 131 | Jensen, R.T., Tatemoto, K., Mutt, V., Lemp, G.F. and Gardner, J.D. Actions of a newly isolated intestinal peptide PHI on pancreatic acini. Am. J. Physiol. 241: G498-G502, 1981. | | 130 | Gardner, J.D. and Jensen, R.T. Regulation of pancreatic exocrine secretion in vitro - the action of secretagogues. Phil. Trans. Royal Society. London. 296: 17-26, 1981. | | 129 | Adachi, H., Rajh, H.M., Tesser, G.I., DePont, J.J.H.H.M., Jensen, R.T. and Gardner, J.D. Interaction of tryptophan-modified analogues of cholecystokinin-octapeptide with cholecystokinin receptors on pancreatic acini. Biochim. Biophys. Acta. 678: 358-363, 1981.
| | 128 | Pan, G.Z., Martinez, J., Bodanszky, M. Jensen, R.T. and Gardner, J.D. The importance of the amino acid in position 32 of cholecystokinin in determining its interaction with cholecystokinin receptors on pancreatic acini. Biochim. Biophys. Acta. 678: 352-357, 1981. | | 127 | Hahne, W.F., Jensen, R.T., Lemp, G.F. and Gardner, J.D. Proglumide and benzotript: Members of a different class of cholecystokinin receptor antagonists. Proc. Natl. Acad. Sci. USA. 78: 6304-6308, 1981. | | 126 | Moroder, L., Wilschowitz, L., Gemeiner, M., Gohring, W., Knof, S., Scharf, R., Thamm, P., Gardner, J.D., Solomon, T.E. and Wunsch, E. Zur Synthese von Cholecystokinin-Pankreozymin. Hoppe-Seyler's Z. Physiol. Chem. 362: 929-942, 1981. | | 125 | Wunsch, E., Moroder, L., Wilschowitz, L., Gohring, W., Scharf, R. and Gardner, J.D. Zur Totalsynthese von Cholecystokinin-Pankreozymin. Hoppe-Seyler's Z. Physiol. Chem. 362: 143-152, 1981. | | 124 | Abdelmoumene, S. and Gardner, J.D. Effect of extracellular manganese on amylase release from dispersed pancreatic acini. Am. J. Physiol. 241: G359-G364, 1981. | | 123 | Collins, S.M., Abdelmoumene, S., Jensen, R.T. and Gardner, J.D. Reversal of cholecystokinin-induced persistent stimulation of pancreatic enzyme secretion by dibutyryl cyclic GMP. Am. J. Physiol. 240: G466-G471, 1981. | | 122 | Collins, S.M., Abdelmoumene, S., Jensen, R.T. and Gardner, J.D. Cholecystokinin-induced persistent stimulation of enzyme secretion in pancreatic acini. Am. J. Physiol. 240: G459-G465, 1981. | | 121 | Jensen, R.T., Collins, S.M., Pandol, S.J. and Gardner, J.D. Lessons from studies of secretagogue receptors on pancreatic acinar cells. In: Gut Hormones. (S.R. Bloom and J.M. Polak, eds.). Churchill Livingstone, Edinburgh, 1981, pp. 133-136. | | 120 | Gardner, J.D. and Jensen, R.T. Regulation of pancreatic enzyme secretion in vitro. In: Physiology of the Gastrointestinal Tract. (L. Johnson, J. Christensen, M. Grossman, E.D. Jacobson and S.G. Schultz, eds.). Raven Press, New York, N.Y., 1981, pp.831-871. | | 119 | Jensen, R.T. and Gardner, J.D. Identification and characterization of receptors for secretagogues on pancreatic acinar cells. Fed. Proc. 40: 2486-2496, 1981. | | 118 | Bodanszky, M., Tolle, J.C., Gardner, J.D., Walker, M.D. and Mutt, V. Cholecystokinin (Pancreozymin): Synthesis and Properties of the Nα-Acetyl-derivative of Cholecystokinin 27-33. Int. J. Pept. Prot. Res. 16: 402-411, 1980. | | 117 | Loveridge, N., Bitensky, L., Chayen, J., Hausamen, T.U., Fisher, J.M., Taylor, K.B., Gardner, J.D., Bottazzo, G.F. and Doniach, D. Inhibition of parietal cell function by human gammaglobulin containing gastric parietal cell antibodies. Clin. Exp. Immunol. 41: 264-270, 1980. | | 116 | Gardner, J.D., Abdelmoumene, S., Lee, P.C., Collins, S.M. and Jensen, R.T. Secretagogue-induced desensitization in pancreatic acinar cells. In: Biology of Exocrine Pancreatic Cell. (A. Ribet, ed.). Elsevier/North-Holland, Amsterdam, 1980, pp.165-170. | | 115 | Korman, L.Y., Walker, M.D. and Gardner, J.D. The action of theophylline on secretagogue-stimulated amylase release from dispersed pancreatic acini. Am. J. Physiol. 239: G324-G333, 1980. | | 114 | Abdelmoumene, S. and Gardner, J.D. Cholecystokinin-induced desensitization in dispersed acini from guinea pig pancreas. Am. J. Physiol. 239: G272-G279, 1980. | | 113 | Gardner, J.D., Walker, M.D., Martinez, J., Priestley, G.P., Natarajan, S. and Bodanszky, M. The importance of the amino acid in position 27 of cholecystokinin in determining its biological activity on pancreatic acinar cells. Biochim. Biophys. Acta. 630: 323-329, 1980. | | 112 | Gardner, J.D., Rottman, A.J., Fink, M.L., Natarajan, S. and Bodanszky, M. Importance of the amino acid in position 15 of VIP and secretin in influencing their interactions with membrane receptors on pancreatic acinar cells. Endocrinologia Japonica, Supp. 1: 1-5, 1980. | | 111 | Loveridge, N., Hoile, R.W., Johnson, A.G., Gardner, J.D. and Chayen, J. The cytochemical section-bioassay of gastrin-like activity. J. Immunoassay 1: 195-209, 1980. | | 110 | Gardner, J.D. Pathogenesis of secretory diarrhea. In: Secretory Diarrhea, (M. Field, J.S. Fordtran and S. Schultz, eds.). Am. Physiol. Soc., Baltimore, Md., 1980, pp.153-158. | | 109 | Pandol, S.J., Korman, L.Y., McCarthy, D.M. and Gardner, J.D. The beneficial effect of oral lithium carbonate in the treatment of pancreatic cholera syndrome. N. Eng. J. Med. 302: 1403-1405, 1980. | | 108 | Gardner, J.D. and Jensen, R.T. Receptors mediating the actions of gastrointestinal peptides and other secretagogues on pancreatic acinar cells. In: Polypeptide Hormones. (R.F. Beers, Jr. and E.G. Bassett, eds.). Raven Press, New York, N.Y., 1980, pp.395-412. | | 107 | Gardner, J.D., Walker, M.D. and Rottman, A.J. Effect of A23187 on amylase release from dispersed acini prepared from guinea pig pancreas. Am. J. Physiol. 238: G458-G466, 1980. | | 106 | Jensen, R.T., Lemp, G.F. and Gardner, J.D. Interaction of cholecystokinin with specific membrane receptors on pancreatic acinar cells. Proc. Natl. Acad. Sci. USA. 77: 2079-2083, 1980. | | 105 | Gardner, J.D. and Rottman, A.J. Evidence against cyclic GMP as a mediator of the actions of secretagogues on amylase release from guinea pig pancreas. Biochim. Biophys. Acta. 627: 230-243, 1980. | | 104 | Lee, P.C., Jensen, R.T. and Gardner, J.D. Bombesin-induced desensitization of enzyme secretion in dispersed acini from guinea pig pancreas. Am. J. Physiol. 238: G213-G218, 1980. | | 103 | Binder, H.J., Lemp, G.F. and Gardner, J.D. Receptors for vasoactive intestinal peptide and secretin on small intestinal epithelial cells. Am. J. Physiol. 238: G190-G196, 1980 | | 102 | Bodanszky, M., Martinez, J., Walker, M., Gardner, J.D. and Mutt, V. Cholecystokinin (pancreozymin) 5.1 Hormonally active desamino derivative of Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2. J. Med. Chem. 23: 82-85, 1980. | | 101 | Gardner, J.D. and Jensen, R.T. Receptors for secretagogues on pancreatic acinar cells. Am. J. Physiol. 238: G63-G66, 1980. | | 100 | Jensen, R.T. and Gardner, J.D. Gastrointestinal peptides: receptors and mechanisms of action in pancreatic acinar cells. In: Peptides: Structure and Biological Function. Proceedings of 6th American Peptide Symposium. (E. Gross and J. Meienhofer, eds.). Pierce Chemical Co., Rockford, Il., 1979, pp.1001-1009. | | 99 | Jensen, R.T. and Gardner, J.D. Interaction of physalaemin, substance P and eledoisin with specific membrane receptors on pancreatic acinar cells. Proc. Natl. Acad. Sci. USA. 76: 5679-5683, 1979. | | 98 | Gardner, J.D. and Jensen, R.T. The physiologic and pharmacologic significance of potentiating interactions among secretagogues. In: Gut Peptides: Secretion, Function and Clinical Aspects. (A. Miyoshi, ed.). Kodansha LTD, Elsevier/North-Holland Biomedical Press, Tokyo, 1979, pp.154-156. | | 97 | Gardner, J.D. and Jensen, R.T. Actions of pancreatic secretagogues in vitro: unresolved issues. In: Gut Peptides: Secretion, Function and Clinical Aspects. (A. Miyoshi, ed.). Kodansha, LTD, Elsevier/North-Holland Biomedical Press, Tokyo, 1979, pp.123-128. | | 96 | Jensen, R.T. and Gardner, J.D. Receptors for secretagogues on pancreatic acinar cells: Different mechanisms of spareness. In: Hormone Receptors in Digestion and Nutrition, (S. Bonfils, P. Fromageot and G. Rosselin, eds.). Elsevier/North-Holland Biomedical Press, North Holland, 1979, pp.167-176. | | 95 | Batzri, S. and Gardner, J.D. Action of histamine on cyclic AMP in guinea pig gastric cells: inhibitions by H1- and H2-receptor antagonists. J. Mol. Pharmacol. 16: 406-416, 1979. | | 94 | Gardner, J.D. Hormones and diarrhea. In: Proceedings of the First International Colloquium in Gastroenterology, Frontiers of Knowledge in the Diarrheal Diseases. (H.D. Janowitz and D.B. Sachar, eds.). Projects in Health, Inc., Upper Montclair, NJ, 1979, pp.279-288. | | 93 | Gardner, J.D. Biochemical basis of action of gastrointestinal hormones. World J. Surg. 3: 407-413, 1979. | | 92 | Olinger, E.J. and Gardner, J.D. Action of VIP and secretin on adenylate cyclase activity in acinar cells from guinea pig pancreas. Gastroenterology 77: 704-713, 1979. | | 91 | Gardner, J.D. and Rottman, A.J. Action of cholera toxin on dispersed acini from guinea pig pancreas. Biochim. Biophys. Acta. 585: 250-265, 1979. | | 90 | Peikin, S.R., Costenbader, C.L. and Gardner, J.D. Actions of derivatives of cyclic nucleotides on dispersed acini from guinea pig pancreas: Discovery of a competitive antagonist of the action of cholecystokinin. J. Biol. Chem. 254: 5321-5327, 1979. | | 89 | Uhlemann, E.R., Robberecht, P. and Gardner, J.D. Effects of alcohols on the actions of VIP and secretin on acinar cells from guinea pig pancreas. Gastroenterology 76: 917-925, 1979. | | 88 | Gardner, J.D., Costenbader, C.L. and Uhlemann, E.R. Effect of extracellular calcium on amylase release from dispersed pancreatic acini. Am. J. Physiol. 236: E754-E762, 1979. | | 87 | Uhlemann, E.R., Rottman, A.J. and Gardner, J.D. Actions of peptides isolated from amphibian skin on amylase release from dispersed pancreatic acini. Am. J. Physiol. 236: E571-E576, 1979. | | 86 | Gardner, J.D., Rottman, A.J., Natarajan, S. and Bodanszky, M. Interaction of secretin5-27 and its analogues with hormone receptors on pancreatic acini. Biochim. Biophys. Acta. 583: 491-503, 1979. | | 85 | Gardner, J.D. Regulation of pancreatic exocrine function in vitro: initial steps in the action of secretagogues. Ann. Rev. Physiol. 41: 55-66, 1979. | | 84 | Gardner, J.D. Receptors for gastrointestinal hormones. Gastroenterology 76: 202-214, 1979. | | 83 | Jensen, R.T., Moody, T., Pert, C., Rivier, J.E. and Gardner, J.D. Interaction of bombesin and litorin with specific membrane receptors on pancreatic acinar cells. Proc. Natl. Acad. Sci. USA. 75: 6139-6143, 1978. | | 82 | Brown, E.M., Spiegel, A.M., Gardner, J.D. and Aurbach, G.D. Direct identification and characterization of β-adrenergic receptors and functional relationship of adenylyl cyclase. In: Receptors and Hormone Action III (L. Birnbaumer and B.W. O'Malley, eds.). Acad. Press, New York, 1978, pp. 101-131. | | 81 | Peikin, S.R., and Rottman, A.J., Batzri, S. and Gardner, J.D. Kinetics of amylase release by dispersed acini prepared from guinea pig pancreas. Am. J. Physiol. 235: 743-750, 1978. | | 80 | Bodanszky, M., Natarajan, S., Gardner, J.D., Makhlouf, G. and Said, S.I. Synthesis and some pharmacological properties of the 23-peptide 15-lysine-secretin 5-27: Special role of the residue in position 15 in biological activity of VIP. J. Med. Chem. 21: 1171-1173, 1978. | | 79 | Bodanszky, M., Martinez, J., Priestley, G.P., Gardner, J.D. and Mutt, V. Cholecystokinin (pancreozymin). IV1Synthesis and properties of a biologically active analogue of the C-terminal 7-peptide with ε-hydroxynorleucine sulfate replacing tyrosine sulfate. J. Med. Chem. 21: 1030-1035, 1978. | | 78 | Gardner, J.D. Receptors and gastrointestinal hormones. In: Gastrointestinal Disease, (M.H. Sleisenger and J.S. Fordtran, eds.). W.B. Saunders and Co. Philadelphia, PA, 1, 1978, pp. 179-195. | | 77 | Jensen, R.T. and Gardner, J.D. Cyclic nucleotide-dependent protein kinase activity in acinar cells from guinea pig pancreas. Gastroenterology 75: 806-816, 1978. | | 76 | Lopatin, R.N. and Gardner, J.D. Effects of calcium on the ability of various agents to increase cyclic GMP in pancreatic acinar cells. Biochim. Biophys. Acta. 543: 465-475, 1978. | | 75 | May, R.J., Conlon, T.P., Erspamer, V. and Gardner, J.D. Actions of peptides isolated from amphibian skin on pancreatic acinar cells. Am. J. Physiol. 235: E112-E118, 1978. | | 74 | Gardner, J.D. Diarrheal syndromes associated with neoplasms. In: Pathophysiology of Diarrhea. (S. Cohen, ed.). Searle Laboratories, San Juan, Puerto Rico, 1978, pp.1-4. | | 73 | Batzri, S. and Gardner, J.D. Potassium transport in dispersed mucosal cells from guinea pig stomach. Biochim. Biophys. Acta. 508: 328-338, 1978. | | 72 | Batzri, S. and Gardner, J.D. Cellular cyclic AMP in dispersed mucosal cells from guinea pig stomach. Biochim. Biophys. Acta. 541: 181-189, 1978. | | 71 | Gardner, J.D., Jackson, M.J., Batzri, S. and Jensen, R.T. Potential mechanisms of interaction among secretagogues. Gastroenterology 74: 348-354, 1978. | | 70 | Gardner, J.D. Plasma VIP in patients with watery diarrhea syndrome. Am. J. Dig. Dis. 23: 370-373, 1978. | | 69 | Gardner, J.D. and McCarthy, D.M. Arguments against vasoactive intestinal peptide being the cause of the watery diarrhea syndrome. In: Gut Hormones. (S. Bloom, ed.). Churchill Livingstone, Edinburgh, London and New York, 1978, pp.570-573. | | 68 | Gardner, J.D., Long, B.W., Uhlemann, E.R. and Peikin, S.R. Membrane receptors for VIP and secretin. In: Gut Hormones. (S. Bloom, ed.). Churchill Livingstone, Edinburgh, London and New York, 1978, pp.92-96. | | 67 | Gardner, J.D. and Hahne, W.F. Calcium transport in dispersed acinar cells from rat pancreas. Biochim. Biophys. Acta. 471: 466-476, 1977. | | 66 | McCarthy, D.M., Ollinger, E.J., May, R.J., Long, B.W. and Gardner, J.D.
H2-histamine receptor blocking agents in the Zollinger-Ellison syndrome: Experience in 7 cases and implications for long term therapy. Ann. Int. Med. 87: 668-675, 1977.
| | 65 | Sjodin, L. and Gardner, J.D. Effect of cholecystokinin variant (CCK39) on dispersed acinar cells from guinea pig pancreas. Gastroenterology 73: 1015-1018, 1977.
| | 64 | Long, B.W. and Gardner, J.D. Effects of cholecystokinin on adenylate cyclase activity in dispersed pancreatic acinar cells. Gastroenterology 73: 1008-1014, 1977. | | 63 | Waldman, D.B., Gardner, J.D., Zfass, A.M. and Makhlouf, G.M. Effects of vasoactive intestinal peptide (VIP), secretin and related peptides on colonic transport and adenylate cyclase activity. Gastroenterology 73: 518-523, 1977. | | 62 | Bodanszky, M., Natarajan, S., Hahne, W. and Gardner, J.D. Cholecystokinin-pancreozymin. III. Synthesis and properties of an analog of the C-terminal heptapeptide with serine-sulfate replacing tyrosine-sulfate. J. Med. Chem. 20: 1047-1050, 1077. | | 61 | Gardner, J.D., Conlon, T.P., Beyerman, H.C. and Van Zon, A. Interaction of synthetic 10-tyrosil analogues of secretin with hormone receptors on pancreatic acinar cells. Gastroenterology 73: 52-56, 1977.
| | 60 | Gardner, J.D. and Jackson, M.J. Regulation of amylase release from dispersed pancreatic acinar cells. J. Physiol. 270: 439-444, 1977. | | 59 | Dubois, A., Natelson, B.H., Van Eerdewegh, P. and Gardner, J.D. Gastric emptying and secretion in the rhesus monkey. Am. J. Physiol. 232: E186-E192, 1977. | | 58 | Gardner, J. D., Christophe, J.P., Conlon, T.P. and Frandsen, E.K. Initial steps in the actin of cholecystokinin and cholinergic agents on pancreatic acinar cells. In: Hormonal Receptors in Digestive Tract Physiology. (S. Bonfils, P. Fromageot and G. Rosselin, eds.). Elsevier/North Holland Biomedical Press, North Holland, 1977, pp.237-246. | | 57 | Gardner, J.D., Christophe, J., Robberecht, P. and Conlon, T.P. Membrane receptors for VIP and secretin in pancreatic acinar cells. In: Hormonal Receptors in Digestive Tract Physiology. (S. Bonfils, P. Fromageot and G. Rosselin, eds.). Elsevier/North-Holland Biomedical Press, North Holland, 1977, pp.227-235. | | 56 | Dubois, A., Van Eerdewegh, P. and Gardner, J.D. Gastric emptying and secretion in Zollinger-Ellison Syndrome. J. Clin. Invest. 59: 255-263, 1977. | | 55 | Dubois, A., Van Eerdewegh, P. and Gardner, J.D. A new method for simultaneous determination of gastric emptying and secretion. In: Proceedings 5th International Symposium on Gastrointestinal Motility. (Van Trappen, ed.). Leuven., 1977, pp.244-247. | | 54 | Shelby, H.T., Gross, L.P., Lichty, P. and Gardner, J.D. Action of cholecystokinin and cholinergic agents on membrane-bound calcium in dispersed pancreatic acinar cells. J. Clin. Invest. 58: 1482-1493, 1976. | | 53 | Brown, E.M., Gardner, J.D. and Aurbach, G.D. Direct determination of ligand interactions with beta-adrenergic receptors on intact turkey erythrocytes: correlation of binding with biological activity. Endocrinology 99: 1369-1376. | | 52 | Batzri, S. and Gardner, J.D. Amino acid transport in isolated rat thymocytes. J. Biol. Chem. 251: 6030-6035, 1976. | | 51 | Christophe, J.P., Frandsen, E.K., Conlon, T.P., Krishna, G. and Gardner, J.D. Action of cholecystokinin, cholinergic agents, and A-23187 on accumulation of guanosine 3':5'-monophosphate in dispersed guinea pig pancreatic acinar cells. J. Biol Chem. 251: 4640-4645, 1976. | | 50 | Robberecht, P., Conlon, T.P. and Gardner, J.D. Interaction of porcine vasoactive intestinal peptide with dispersed pancreatic acinar cells from the guinea pig. Structural requirements for effects of vasoactive intestinal peptide and secretin on cellular adenosine 3':5'-monophosphate. J. Biol. Chem. 251: 4635-4639, 1976. | | 49 | Christophe, J.P., Conlon, T.P. and Gardner, J.D. Interaction of porcine vasoactive intestinal peptide with dispersed pancreatic acinar cells from the guinea pig. Binding of radioiodinated peptide. J. Biol. Chem. 251: 4629-4634, 1976. | | 48 | Gardner, J.D., Conlon, T.P., Fink, M.L. and Bodanszky, M. Interaction of peptides related to secretin with hormone receptors on pancreatic acinar cells. Gastroenterology 71: 965-970, 1976. | | 47 | Olinger, E.J., McCarthy, D.M., Young, R.C. and Gardner, J.D. Hyperhistaminemia and hyperchlorhydria in basophilic granulocytic leukemia. Gastroenterology 71: 667-669, 1976. | | 46 | Christophe, J.P., Conlon, T.P., Robberecht, P. and Gardner, J.D. The specific binding and action of vasoactive intestinal peptide (VIP) on isolated pancreatic acinar cells. In: Stimulus-Secretion Coupling in the Gastrointestinal Tract. (R.M. Case and H. Goebell, eds.). Univ. Park Press, Baltimore, MD., 1976, pp.377-380. | | 45 | Christophe, J.P., Frandsen, E.K., Conlon, T.P., Krishna, G. and Gardner, J.D. Factors Regulating Cyclic GMP Levels in Isolated Pancreatic Acinar Cells. In: Stimulus-Secretion Coupling in the Gastrointestinal Tract. (R.M. Case and H. Goebell, eds.). Univ. Park Press, Baltimore, Md. 1976, pp.233-235. | | 44 | Gardner, J.D., Aurbach, G.D., Spiegel, A.M. and Brown, E.M. Receptor function and ion transport in turkey erythrocytes. Recent Prog. Horm. Res. 32: 567-595, 1976. | | 43 | Aurbach, G.D., Brown, E., Spiegel, A.M. and Gardner, J.D. Beta-adrenergic receptors, cyclic AMP and ion transport in the avian erythrocyte. In: Cell Membrane Receptors for Viruses, Antigens and Antibodies, Polypeptide Hormones and Small Molecules. (R.F. Beers, Jr. and E.G. Bassett, eds.). Proc. 9th Miles Int. Symp., Raven Press, New York, 1976, pp.379-392. | | 42 | Levy, A.G., Widerlite, L. Schwartz, C.J., Dolin, R., Blacklow, N.R., Gardner, J.D., Kimberg, D.V. and Trier, J.S. Jejunal adenylate cyclase activity in human subjects during viral gastroenteritis. Gastroenterology 70: 321-325, 1976. | | 41 | Gardner, J.D., Conlon, T.P. and Adams, T.D. Cyclic AMP in pancreatic acinar cells: Effects of gastrointestinal hormones. Gastroenterology 70: 29-35, 1976. | | 40 | Dolin, R., Levy, A.G., Wyatt, R.G., Thornhill, T.S. and Gardner, J.D. Viral gastroenteritis induced by the Hawaii agent. Am. J. Med. 59: 761-768, 1975. | | 39 | Gardner, J.D. Pancreatic cholera. Editorial. Western J. Med. 123: 309-310, 1975. | | 38 | Gardner, J.D., Conlon, T.P., Klaeveman, H.L., Adams, T.D. and Ondetti, M.A. Action of cholecystokinin and cholinergic agents on calcium transport in isolated pancreatic acinar cells. J. Clin. Invest. 56: 366-375, 1975. | | 37 | Klaeveman, H.L., Conlon, T.P. and Gardner, J.D. Effects of gastrointestinal hormones on adenylate cyclase activity in pancreatic exocrine cells. In: Gastrointestinal Hormones (J.C. Thompson, ed.). Univ. of Texas Press, Austin, 1975, pp.321-344. | | 36 | Klaeveman, H.L., Conlon, T.P., Levy, A.G. and Gardner, J.D. Effects of gastrointestinal hormones on adenylate cyclase activity in human jejunal mucosa. Gastroenterology 68: 667-675, 1975. | | 35 | Kahn, C.R., Levy, A.G., Gardner, J.D., Miller, J.V., Gorden, P. and Schein, P.S. Pancreatic cholera: beneficial effects of treatment with streptozotocin. New Eng. J. Med. 292: 941-945, 1975. | | 34 | Aurbach, G.D., Spiegel, A.M. and Gardner, J.D. β-Adrenergic receptors, cyclic AMP, and ion transport in the avian erythrocyte. In: Advances in Cyclic Nucleotide Research, 5, (G.I. Drummond, P. Greengard and G.A. Robison, eds.). Raven Press, New York, 1975, pp.117-132. | | 33 | Gardner, J.D., Jow, N. and Kiino, D.R. Refractoriness of cation transport in turkey erythrocytes to stimulation by cyclic adenosine 3':5'-monophosphate. J. Biol. Chem. 250: 1176-1185, 1975. | | 32 | Gardner, J.D., Mensh, R.S., Kiino, D.R. and Aurbach, G.D. Effects of β-adrenergic catecholamines on potassium transport in turkey erythrocytes. J. Biol. Chem. 250: 1176-1185, 1975. | | 31 | Gardner, J.D., Kiino, D.R., Jow, N. and Aurbach, G.D. Effects of extracellular cations and ouabain on catecholamine-stimulated sodium and potassium fluxes in turkey erythrocytes. J. Biol. Chem. 250: 1164-1175, 1975. | | 30 | Aurbach, G.D., Bilezikian, J.P. Klaeveman, H.L. and Gardner, J.D. The beta-adrenergic receptor and cyclic AMP-mediated sodium transport in the avian erythrocyte. In: Endocrinology (Taylor, S., ed.). William Heinemann Medical Books, Ltd., London, 1974, pp.343-348. | | 29 | Butler, V.P., Jr., Schmidt, D.H., Watson, J.F. and Gardner, J.D. Production and properties of digoxin-specific antibodies. Ann. N.Y. Acad. Sci. 242: 717-730, 1974. | | 28 | Gardner, J.D., Klaeveman, H.L., Bilezikian, J.P. and Aurbach, G.D. Stimulation of sodium transport in turkey erythrocytes by cyclic 3',5'-AMP. Endocrinology 96: 499-507, 1974. | | 27 | Gardner, J.D., Klaeveman, H.L., Bilezikian, J.P. and Aurbach, G.D. Effects of ouabain on catecholamine-stimulated sodium transport in turkey erythrocytes. J. Biol. Chem. 248: 516-520, 1974. | | 26 | Boyle, J.M. and Gardner, J.D. Sequence of events mediating the effect of cholera toxin on rat thymocytes. J. Clin. Invest. 53: 1149-1158, 1974. | | 25 | Gardner, J.D. and Frantz, C. Effects of cations on ouabain binding by intact human erythrocytes. J. Memb. Biol. 16: 43-64, 1974. | | 24 | Gardner, J.D., Klaeveman, H.L., Bilezikian, J.P. and Aurbach, G.D. Effect of β-adrenergic catecholamines on sodium transport in turkey erythrocytes. J. Biol. Chem. 248: 5590-5597, 1973. | | 23 | Butler, V.P., Jr., Watson, J.F., Schmidt, D.H., Gardner, J.D., Mandel, W.J. and Skelton, C.L. Reversal of the pharmacological and toxic effects of cardiac glycosides by specific antibodies. Pharm. Rev. 25: 239-248, 1973.
| | 22 | Gardner, J.D., Kiino, D.R., Swartz, T.J. and Butler, V.P., Jr. Effects of digoxin-specific antibodies on the accumulation and binding of digoxin by human erythrocytes. J. Clin. Invest. 52: 1820-1833, 1973. | | 21 | Gardner, J.D. and Kiino, D.R. Ouabain binding and cation transport in human erythrocytes. J. Clin. Invest. 52: 1845-1851, 1973. | | 20 | Gardner, J.D. and Conlon, T.P. The effects of sodium and potassium on ouabain binding by human erythrocytes. J. Gen. Physiol. 60: 609-629, 1972. | | 19 | Goldfine, I.D., Gardner, J.D. and Neville, D.M., Jr. Insulin action in isolated rat thymocytes. I. Binding of 125I-insulin and stimulation of α-aminoisobutyric acid transport. J. Biol. Chem. 247: 6919-6926, 1972.
| | 18 | Hadler, N.M., Gill, J.R., Jr., and Gardner, J.D. Impaired renal tubular secretion of potassium, elevated sweat sodium chloride concentration, and plasma inhibition of erythrocyte sodium outflux as a complication of systemic lupus erythematosus. Arth. Rheum. 15: 515-523, 1972. | | 17 | Gordon, R.S., Jr., Gardner, J.D. and Kinzie, J.L. Low mannitol clearance into cholera stool as evidence against filtration as the source of stool fluid. Gastroenterology 63: 407-412, 1972. | | 16 | Taussig, L.M. and Gardner, J.D. Effects of saliva and plasma from cystic fibrosis patients on membrane transport. Lancet 1: 1367-1369, 1972. | | 15 | Gardner, J.D., Simopoulos, A.P., Lapey, A. and Shibolet, S. Altered membrane sodium transport in Bartter's syndrome. J. Clin. Invest. 51: 1565-1571, 1972. | | 14 | Gardner, J.D., Shibolet, S. and Ginzler, E.R. A two-site model for sodium transport in rabbit erythrocytes. Biochem. Biophys. Res. Comm. 46: 1361-1367, 1972. | | 13 | Gardner, J.D. and Levy, A.G. Transport of dibasic amino acids by human erythrocytes. Metabolism 21: 413-431, 1972. | | 12 | Gardner, J.D., Shibolet, S. and Ginzler, E.R. A two-site model for sodium transport in human erythrocytes. Biochem. Biophys. Res. Comm. 45: 1548-1553, 1971. | | 11 | Shibolet, S. and Gardner, J.D. Effect of temperature on sodium transport in human erythrocytes in vitro. Am. J. Physiol. 221: 1358-1360, 1971. | | 10 | Gardner, J.D., Lapey, A., Simopoulos, A.P. and Bravo, E.L. Abnormal membrane sodium transport in Liddle's syndrome. J. Clin. Invest. 50: 2253-2258, 1971. | | 9 | Lapey, A. and Gardner, J.D. Abnormal erythrocyte sodium transport in cystic fibrosis. Ped. Res. 5: 446-451, 1971. | | 8 | Gardner, J.D. and Lapey, A. Sodium outflux and ATPase activity in human and rabbit erythrocytes. J. Appl. Physiol. 31: 161-163, 1971. | | 7 | Gardner, J.D. and Ginzler, E.R. Sodium transport in human erythrocytes--absence of an effect of prostaglandin E1. Biochem. Biophys. Res. Comm. 42: 1063-1067, 1971. | | 6 | Gardner, J.D., Brown, M.S. and Laster, L. The columnar epithelial cell of the small intestine: Digestion and transport. New Eng. J. Med. 283: 1196-1202, 1264-1271, 1317-1324, 1970. | | 5 | DaCruz, G.M.G., Gardner, J.D. and Peskin, G.W. Mechanism of diarrhea of villous adenomas. Am. J. Surg. 115: 203-208, 1968. | | 4 | DaCruz, G.M.G., Gardner, J.D. and Peskin, G.W. Influence of gastrointestinal tumors on intestinal absorption. Surg. Forum. 18: 336-338, 1967. | | 3 | Gardner, J.D. and Cerda, J.J. In vitro inhibition of intestinal fluid and electrolyte transfer by a non-beta islet cell tumor. Proc. Soc. Exptl. Biol. Med. 123: 361-364, 1966. | | 2 | Gardner, J.D. and Peskin, G.W. Problems in intestinal absorption. Am. J. Med. Sci. 251: 225-235, 1966 | | 1 | Gardner, J.D., Peskin, G.W., Cerda, J.J. and Brooks, F.P. Alterations of in vitro fluid and electrolyte absorption by gastrointestinal hormones. Am. J. Surg. 113: 57-64, 1966. |
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